Glycoprotein Activating Factors are substances that are designed to stimulate or activate specific glycoproteins in the skin. These glycoproteins play important roles in various cellular processes, including cell communication, growth, and repair

Our transdermal glycoprotein activating factor cream with a special formula is designed to deliver the active ingredient through the skin’s barrier and into the bloodstream while maintaining stability and effectiveness

Our transdermal glycoprotein activating factor cream employs a sophisticated formulation designed for efficient skin penetration and absorption. The active ingredient, the glycoprotein activating factor, is incorporated into the cream in a manner that allows it to traverse the skin’s outermost layer, the epidermis. This is achieved through the use of our specialized formula, that release the active ingredient directly into the epidermal layers where it can engage with specific glycoproteins present on the cell surfaces. This targeted interaction within the epidermis helps initiate various cellular processes, promoting skin health and rejuvenation.

Furthermore, the transdermal nature of our cream enables the glycoprotein activating factor to reach the lymphatic system. As the glycoprotein activating factor interacts with skin cells and gets absorbed into the epidermis, it can potentially permeate deeper layers and enter the lymphatic vessels that are intertwined within the skin. The lymphatic system serves as a crucial part of the body’s immune and circulatory systems, carrying immune cells and waste products away from tissues. By reaching the lymphatic system, the glycoprotein activating factor can be transported to other parts of the body, contributing to its broader systemic effects, and potentially assisting in overall health and well-being. This comprehensive approach to transdermal delivery ensures that the glycoprotein activating factor in our cream can benefit not only the skin but also the body as a whole.


Sublingual administration is a method of delivering vitamins or nutrients by placing them under the tongue, where they are absorbed directly into the bloodstream through the sublingual mucosa, bypassing the digestive system. This route of administration is often chosen when certain vitamins or nutrients are not effectively absorbed when taken orally and broken down in the stomach. Here’s how sublingual administration works and why it can be more effective than oral ingestion:

  1. Rapid Absorption: The sublingual mucosa, located under the tongue, is highly vascularized and contains many blood vessels. When a vitamin or nutrient is placed under the tongue, it dissolves in the saliva and is quickly absorbed into these blood vessels. This direct absorption allows for rapid delivery of the substance into the bloodstream, bypassing the digestive system, where degradation can occur.
  2. Bypassing the Digestive System: When you ingest vitamins or nutrients orally, they must pass through the stomach and intestines before entering the bloodstream. During this journey, they can be exposed to stomach acid and digestive enzymes, which can break them down and reduce their effectiveness. Sublingual administration avoids this digestive process, ensuring a higher bioavailability of the nutrient.
  3. Avoiding First-Pass Metabolism: Substances absorbed through the digestive system may undergo “first-pass metabolism” in the liver, where they can be partially metabolized before reaching systemic circulation. Sublingual administration bypasses the liver initially, allowing more of the active ingredient to reach the bloodstream intact.
  4. Enhanced Bioavailability: Because sublingual administration allows for a greater proportion of the nutrient to enter the bloodstream directly, it often results in higher bioavailability. This means that a smaller dose of the nutrient can be as effective as a larger dose taken orally.
  5. Better for Sensitive Nutrients: Some vitamins and nutrients are particularly sensitive to the acidic environment of the stomach, and they may degrade when exposed to gastric acid. Sublingual administration can help protect these sensitive compounds.

It’s important to note that our GlycoPlus (glycoprotein macrophage activating factor) has been specifically created to be effectively administered sublingually.

Not all vitamins and nutrients can be effectively administered sublingually.